Phenotypes associated with this allele

• Allele Symbol: Slc22a4^tm1Atsu
• Allele Name: targeted mutation 1, Akira Tsuji
• Allele ID: MGI:5554255
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc22a4^tm1Atsu/Slc22a4^tm1Atsu	involves: C57BL/6J	MGI:5554286

Genotype
MGI:5554286

hm1

• Allelic Composition: Slc22a4^tm1Atsu/Slc22a4^tm1Atsu
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to induced morbidity/mortality ( J:207006 )

• after ischemia and reperfusion in the small intestine

digestive/alimentary system

abnormal small intestinal villus morphology ( J:207006 )

• loss of small intestine villi after ischemia and reperfusion in the small intestine

intestinal inflammation ( J:207006 )

• after ischemia and reperfusion in the small intestine

homeostasis/metabolism

abnormal amino acid level ( J:207006 )

• mice exhibit a complete loss of ergothioneine with reduced absorption and increased excretion

increased susceptibility to injury ( J:207006 )

• after ischemia and reperfusion in the small intestine, mice exhibit increased lethality, increased intestinal inflammation and loss of small intestine villi compared with wild-type mice

immune system

intestinal inflammation ( J:207006 )

• after ischemia and reperfusion in the small intestine