All Phenotypes Igh-J<tm3.1(48d)Lave> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Igh-J^{tm3.1(48d)Lave}
targeted mutation 3.1, Laurent Verkoczy
MGI:5550247

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Igh-J^{tm3.1(48d)Lave}/Igh-J^{tm3.1(48d)Lave}	involves: C57BL/6	MGI:5550250

Allelic Composition	Igh-J^{tm3.1(48d)Lave}/Igh-J^{tm3.1(48d)Lave}
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igh-J^{tm3.1(48d)Lave} mutation (0 available); any Igh-J mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:205708 )

N	• mice exhibit normal bone marrow and splenic B cell subset frequencies

decreased B-1a cell number ( J:205708 )

decreased IgG1 level ( J:205708 )

decreased IgG2b level ( J:205708 )

decreased IgM level ( J:205708 )

hematopoietic system

decreased B-1a cell number ( J:205708 )

decreased IgG1 level ( J:205708 )

decreased IgG2b level ( J:205708 )

decreased IgM level ( J:205708 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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