Phenotypes associated with this allele

• Allele Symbol: Xbp1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548973
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Xbp1^tm1b(EUCOMM)Wtsi/Xbp1^tm1b(EUCOMM)Wtsi	C57BL/6N-Xbp1^tm1b(EUCOMM)Wtsi/Ics	MGI:5757893
ht2	Xbp1^tm1b(EUCOMM)Wtsi/Xbp1^+	C57BL/6N-Xbp1^tm1b(EUCOMM)Wtsi/Ics	MGI:5797919

Genotype
MGI:5757893

hm1

• Allelic Composition: Xbp1^{tm1b(EUCOMM)Wtsi}/Xbp1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Xbp1^{tm1b(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0038_2_E10

Data Sources

IMPC Data for Xbp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5797919

ht2

• Allelic Composition: Xbp1^{tm1b(EUCOMM)Wtsi}/Xbp1⁺
• Genetic Background: C57BL/6N-Xbp1^{tm1b(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0038_2_E10

Data Sources

IMPC Data for Xbp1

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - HAR

increased mean corpuscular volume ( J:211773 )

♂

IMPC - HAR

decreased red blood cell distribution width ( J:211773 )

♀

IMPC - HAR

decreased leukocyte cell number ( J:211773 )

♀

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

decreased large unstained cell number ( J:211773 )

♀

IMPC - HAR

immune system

decreased leukocyte cell number ( J:211773 )

♀

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

decreased large unstained cell number ( J:211773 )

♀

IMPC - HAR

vision/eye

persistence of hyaloid vascular system ( J:211773 )

IMPC - HAR