Phenotypes associated with this allele

• Allele Symbol: Col4a5^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548921
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col4a5^tm1b(EUCOMM)Wtsi/Col4a5^tm1b(EUCOMM)Wtsi	C57BL/6N-Col4a5^tm1b(EUCOMM)Wtsi/Cnrm	MGI:5756899
ot2	Col4a5^tm1b(EUCOMM)Wtsi/Y	C57BL/6N-Col4a5^tm1b(EUCOMM)Wtsi/Cnrm	MGI:5756898

Genotype
MGI:5756899

hm1

• Allelic Composition: Col4a5^{tm1b(EUCOMM)Wtsi}/Col4a5^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Col4a5^{tm1b(EUCOMM)Wtsi}/Cnrm
• Cell Lines: EPD0233_5_G04

Data Sources

IMPC Data for Col4a5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♀

IMPC - HAR

growth/size/body

increased spleen weight ( J:211773 )

♀

IMPC - HAR

hematopoietic system

increased spleen weight ( J:211773 )

♀

IMPC - HAR

decreased erythrocyte cell number ( J:211773 )

♀

IMPC - HAR

decreased hematocrit ( J:211773 )

♀

IMPC - HAR

decreased hemoglobin content ( J:211773 )

♀

IMPC - HAR

increased red blood cell distribution width ( J:211773 )

♀

IMPC - HAR

increased neutrophil cell number ( J:211773 )

♀

IMPC - HAR

thrombocytosis ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

♀

IMPC - HAR

increased blood urea nitrogen level ( J:211773 )

♀

IMPC - HAR

decreased circulating fructosamine level ( J:211773 )

♀

IMPC - HAR

increased circulating cholesterol level ( J:211773 )

♀

IMPC - HAR

increased circulating HDL cholesterol level ( J:211773 )

♀

IMPC - HAR

increased circulating triglyceride level ( J:211773 )

♀

IMPC - HAR

increased circulating calcium level ( J:211773 )

♀

IMPC - HAR

increased circulating phosphate level ( J:211773 )

♀

IMPC - HAR

increased circulating amylase level ( J:211773 )

♀

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - HAR

decreased circulating total protein level ( J:211773 )

♀

IMPC - HAR

impaired glucose tolerance ( J:211773 )

♀

IMPC - HAR

immune system

increased spleen weight ( J:211773 )

♀

IMPC - HAR

increased neutrophil cell number ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - HAR

Genotype
MGI:5756898

ot2

• Allelic Composition: Col4a5^{tm1b(EUCOMM)Wtsi}/Y
• Genetic Background: C57BL/6N-Col4a5^{tm1b(EUCOMM)Wtsi}/Cnrm
• Cell Lines: EPD0233_5_G04

Data Sources

IMPC Data for Col4a5

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - HAR

decreased hematocrit ( J:211773 )

♂

IMPC - HAR

decreased hemoglobin content ( J:211773 )

♂

IMPC - HAR

decreased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - HAR

decreased mean corpuscular volume ( J:211773 )

♂

IMPC - HAR

thrombocytosis ( J:211773 )

♂

IMPC - HAR

increased leukocyte cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

♂

IMPC - HAR

increased blood urea nitrogen level ( J:211773 )

♂

IMPC - HAR

decreased circulating fructosamine level ( J:211773 )

♂

IMPC - HAR

increased circulating cholesterol level ( J:211773 )

♂

IMPC - HAR

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - HAR

increased circulating triglyceride level ( J:211773 )

♂

IMPC - HAR

increased circulating calcium level ( J:211773 )

♂

IMPC - HAR

increased circulating amylase level ( J:211773 )

♂

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

decreased circulating total protein level ( J:211773 )

♂

IMPC - HAR

immune system

increased leukocyte cell number ( J:211773 )

♂

IMPC - HAR

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - HAR

vision/eye

abnormal lens morphology ( J:211773 )

♂

IMPC - HAR

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HAR