Phenotypes associated with this allele

• Allele Symbol: Afap1l2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548752
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Afap1l2^tm1b(KOMP)Wtsi/Afap1l2^tm1b(KOMP)Wtsi	C57BL/6N-Afap1l2^tm1b(KOMP)Wtsi/Ucd	MGI:5630834

Genotype
MGI:5630834

hm1

• Allelic Composition: Afap1l2^{tm1b(KOMP)Wtsi}/Afap1l2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Afap1l2^{tm1b(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0107_1_A02

Data Sources

IMPC Data for Afap1l2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - UCD

behavior/neurological

increased startle reflex ( J:211773 )

IMPC - UCD

decreased locomotor activity ( J:211773 )

IMPC - UCD

cardiovascular system

decreased heart rate ( J:211773 )

IMPC - UCD

prolonged RR interval ( J:211773 )

♂

IMPC - UCD

prolonged QRS complex duration ( J:211773 )

IMPC - UCD

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - UCD

hematopoietic system

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - UCD

improved glucose tolerance ( J:211773 )

IMPC - UCD

immune system

increased neutrophil cell number ( J:211773 )

♀

IMPC - UCD

abnormal spleen morphology ( J:211773 )

♀

IMPC - UCD

integument

abnormal coat/ hair morphology ( J:211773 )

♂

IMPC - UCD

skeleton

increased bone mineral content ( J:211773 )

♂

IMPC - UCD