Phenotypes associated with this allele

• Allele Symbol: Wsb2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548747
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wsb2^tm1b(EUCOMM)Hmgu/Wsb2^tm1b(EUCOMM)Hmgu	C57BL/6N-Wsb2^tm1b(EUCOMM)Hmgu/Cnrm	MGI:5757891

Genotype
MGI:5757891

hm1

• Allelic Composition: Wsb2^{tm1b(EUCOMM)Hmgu}/Wsb2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Wsb2^{tm1b(EUCOMM)Hmgu}/Cnrm
• Cell Lines: HEPD0508_2_A11

Data Sources

IMPC Data for Wsb2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased food intake ( J:211773 )

IMPC - HMGU

increased grip strength ( J:211773 )

♀

IMPC - HMGU

decreased vertical activity ( J:211773 )

IMPC - HMGU

decreased locomotor activity ( J:211773 )

♀

IMPC - HMGU

hyperactivity ( J:211773 )

♀

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

decreased cardiac muscle contractility ( J:211773 )

♀

IMPC - HMGU

decreased heart rate ( J:211773 )

IMPC - HMGU

craniofacial

abnormal tooth morphology ( J:211773 )

IMPC - HMGU

growth/size/body

abnormal tooth morphology ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU

decreased respiratory quotient ( J:211773 )

IMPC - HMGU

muscle

decreased cardiac muscle contractility ( J:211773 )

♀

IMPC - HMGU

reproductive system

female infertility ( J:211773 )

♀

IMPC - HMGU

male infertility ( J:211773 )

♂

IMPC - HMGU

skeleton

abnormal tooth morphology ( J:211773 )

IMPC - HMGU

vision/eye

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

decreased total retina thickness ( J:211773 )

IMPC - HMGU