Phenotypes associated with this allele

• Allele Symbol: Pfn4^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548626
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pfn4^tm1b(KOMP)Wtsi/Pfn4^tm1b(KOMP)Wtsi	C57BL/6N-Pfn4^tm1b(KOMP)Wtsi/MbpMmucd	MGI:6461524
hm2	Pfn4^tm1b(KOMP)Wtsi/Pfn4^tm1b(KOMP)Wtsi	C57BL/6N-Pfn4^tm1b(KOMP)Wtsi/Ucd	MGI:6370424

Genotype
MGI:6461524

hm1

• Allelic Composition: Pfn4^{tm1b(KOMP)Wtsi}/Pfn4^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Pfn4^{tm1b(KOMP)Wtsi}/MbpMmucd
• Cell Lines: EPD0500_1_C02

Data Sources

IMPC Data for Pfn4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased bronchoconstrictive response ( J:211773 )

♂

IMPC - TCP

respiratory system

decreased bronchoconstrictive response ( J:211773 )

♂

IMPC - TCP

increased pulmonary respiratory rate ( J:211773 )

♀

IMPC - TCP

decreased pulmonary ventilation ( J:211773 )

IMPC - TCP

Genotype
MGI:6370424

hm2

• Allelic Composition: Pfn4^{tm1b(KOMP)Wtsi}/Pfn4^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Pfn4^{tm1b(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0500_1_C02

Data Sources

IMPC Data for Pfn4

limbs/digits/tail

abnormal tail morphology ( J:211773 )

IMPC - UCD