Phenotypes associated with this allele

• Allele Symbol: Nbas^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548607
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nbas^tm1b(EUCOMM)Hmgu/Nbas^tm1b(EUCOMM)Hmgu	C57BL/6N-Nbas^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262970
ht2	Nbas^tm1b(EUCOMM)Hmgu/Nbas^+	C57BL/6N-Nbas^tm1b(EUCOMM)Hmgu/Ieg	MGI:6262969

Genotype
MGI:6262970

hm1

• Allelic Composition: Nbas^{tm1b(EUCOMM)Hmgu}/Nbas^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Nbas^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0716_4_B11

Data Sources

IMPC Data for Nbas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6262969

ht2

• Allelic Composition: Nbas^{tm1b(EUCOMM)Hmgu}/Nbas⁺
• Genetic Background: C57BL/6N-Nbas^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0716_4_B11

Data Sources

IMPC Data for Nbas

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - HMGU

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU

abnormal retina morphology ( J:211773 )

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

abnormal vitreous body morphology ( J:211773 )

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

IMPC - HMGU