Phenotypes associated with this allele

• Allele Symbol: Ppp6c^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5548551
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ppp6c^tm1b(EUCOMM)Hmgu/Ppp6c^tm1b(EUCOMM)Hmgu	C57BL/6N-Ppp6c^tm1b(EUCOMM)Hmgu/Ics	MGI:5757554
ht2	Ppp6c^tm1b(EUCOMM)Hmgu/Ppp6c^+	C57BL/6N-Ppp6c^tm1b(EUCOMM)Hmgu/Ics	MGI:5757553

Genotype
MGI:5757554

hm1

• Allelic Composition: Ppp6c^{tm1b(EUCOMM)Hmgu}/Ppp6c^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Ppp6c^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0527_7_D10

Data Sources

IMPC Data for Ppp6c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5757553

ht2

• Allelic Composition: Ppp6c^{tm1b(EUCOMM)Hmgu}/Ppp6c⁺
• Genetic Background: C57BL/6N-Ppp6c^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0527_7_D10

Data Sources

IMPC Data for Ppp6c

behavior/neurological

abnormal locomotor behavior ( J:211773 )

♀

IMPC - ICS

abnormal vocalization ( J:211773 )

IMPC - ICS

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - ICS

hematopoietic system

increased mean corpuscular volume ( J:211773 )

IMPC - ICS

homeostasis/metabolism

decreased blood urea nitrogen level ( J:211773 )

IMPC - ICS

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - ICS

limbs/digits/tail

short tibia ( J:211773 )

♂

IMPC - ICS

skeleton

short tibia ( J:211773 )

♂

IMPC - ICS