Phenotypes associated with this allele

• Allele Symbol: Gtpbp2^{tm1b(KOMP)Mbp}
• Allele Name: targeted mutation 1b, Mouse Biology Program, UC Davis
• Allele ID: MGI:5548500
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gtpbp2^tm1b(KOMP)Mbp/Gtpbp2^tm1b(KOMP)Mbp	C57BL/6N-Gtpbp2^tm1b(KOMP)Mbp/Ucd	MGI:5757209
ht2	Gtpbp2^tm1b(KOMP)Mbp/Gtpbp2^+	C57BL/6N-Gtpbp2^tm1b(KOMP)Mbp/Ucd	MGI:5759265

Genotype
MGI:5757209

hm1

• Allelic Composition: Gtpbp2^{tm1b(KOMP)Mbp}/Gtpbp2^{tm1b(KOMP)Mbp}
• Genetic Background: C57BL/6N-Gtpbp2^{tm1b(KOMP)Mbp}/Ucd
• Cell Lines: DEPD00516_2_G07

Data Sources

IMPC Data for Gtpbp2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased exploration in new environment ( J:211773 )

♀

IMPC - TCP

hyperactivity ( J:211773 )

♀

IMPC - TCP

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - TCP

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

vision/eye

abnormal retina vasculature morphology ( J:211773 )

IMPC - TCP

Genotype
MGI:5759265

ht2

• Allelic Composition: Gtpbp2^{tm1b(KOMP)Mbp}/Gtpbp2⁺
• Genetic Background: C57BL/6N-Gtpbp2^{tm1b(KOMP)Mbp}/Ucd
• Cell Lines: DEPD00516_2_G07

Data Sources

IMPC Data for Gtpbp2

immune system

enlarged lymph nodes ( J:211773 )

IMPC - TCP