Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt10atm1.1(KOMP)Vlcg mutation
(1 available);
any
Wnt10a mutation
(19 available)
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Data Sources
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adipose tissue
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IMPC - UCD
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growth/size/body
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IMPC - UCD
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integument
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IMPC - UCD
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limbs/digits/tail
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IMPC - UCD
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pigmentation
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IMPC - UCD
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skeleton
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IMPC - UCD
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt10atm1.1(KOMP)Vlcg mutation
(1 available);
any
Wnt10a mutation
(19 available)
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craniofacial
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• dental pulp calcification
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• taurodontic molar root morphology of all three molars with elongated root trunks and low or absent furcation in the first and second molar
• vertically elongated pulp chamber with very little root canals
• external root resorption
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• V-shaped density defect in the lingual side of the apical end of incisors
• single gap lingually or two gaps depending upon whether a single or double wedge deficiency has formed
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• reduced mesio-distal dimension one first molar with a rounded-square shape
• reduced occlusal table, especially first molars, with decreased mesio-distal dimensions and convergent cusp pattern
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• cusp 4 is absent from the first molar
• three buccal casups (B1-3) and the first lingual cusp (L1) are fused
• smaller L2 and L3 lingual cusps
• deep U-shaped groove surrounding the second lingual cusp (L2) with a blackening carious appearance in one mouse
• molar 2 lacks cusp 4
• irregular concavities of molars
• however, molar 3 has normal crown morphology and cusp pattern
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• small second and third molar
• reduced tooth volume
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• small fourth mandibular molar with a single cusp and thin root in one mouse with residual extra sockets in other mice indicating loss of fourth molars
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• delayed or defective dentin mineralization at the lingual surface of mandibular incisor
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• external root resorption
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growth/size/body
|
|
• dental pulp calcification
|
|
|
• vertically elongated pulp chamber with very little root canals
• external root resorption
• taurodontic molar root morphology of all three molars with elongated root trunks and low or absent furcation in the first and second molar
|
|
|
• V-shaped density defect in the lingual side of the apical end of incisors
• single gap lingually or two gaps depending upon whether a single or double wedge deficiency has formed
|
|
|
• reduced mesio-distal dimension one first molar with a rounded-square shape
• reduced occlusal table, especially first molars, with decreased mesio-distal dimensions and convergent cusp pattern
|
|
|
• cusp 4 is absent from the first molar
• three buccal casups (B1-3) and the first lingual cusp (L1) are fused
• smaller L2 and L3 lingual cusps
• deep U-shaped groove surrounding the second lingual cusp (L2) with a blackening carious appearance in one mouse
• molar 2 lacks cusp 4
• irregular concavities of molars
• however, molar 3 has normal crown morphology and cusp pattern
|
|
|
• small second and third molar
• reduced tooth volume
|
|
|
• small fourth mandibular molar with a single cusp and thin root in one mouse with residual extra sockets in other mice indicating loss of fourth molars
|
|
|
• delayed or defective dentin mineralization at the lingual surface of mandibular incisor
|
|
|
• external root resorption
|
skeleton
|
|
• dental pulp calcification
|
|
|
• taurodontic molar root morphology of all three molars with elongated root trunks and low or absent furcation in the first and second molar
• vertically elongated pulp chamber with very little root canals
• external root resorption
|
|
|
• V-shaped density defect in the lingual side of the apical end of incisors
• single gap lingually or two gaps depending upon whether a single or double wedge deficiency has formed
|
|
|
• reduced mesio-distal dimension one first molar with a rounded-square shape
• reduced occlusal table, especially first molars, with decreased mesio-distal dimensions and convergent cusp pattern
|
|
|
• cusp 4 is absent from the first molar
• three buccal casups (B1-3) and the first lingual cusp (L1) are fused
• smaller L2 and L3 lingual cusps
• deep U-shaped groove surrounding the second lingual cusp (L2) with a blackening carious appearance in one mouse
• molar 2 lacks cusp 4
• irregular concavities of molars
• however, molar 3 has normal crown morphology and cusp pattern
|
|
|
• small second and third molar
• reduced tooth volume
|
|
|
• small fourth mandibular molar with a single cusp and thin root in one mouse with residual extra sockets in other mice indicating loss of fourth molars
|
|
|
• delayed or defective dentin mineralization at the lingual surface of mandibular incisor
|
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• external root resorption
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Analysis Tools