Phenotypes associated with this allele

• Allele Symbol: Fkbp5^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548348
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fkbp5^tm1b(KOMP)Wtsi/Fkbp5^tm1b(KOMP)Wtsi	C57BL/6N-Fkbp5^tm1b(KOMP)Wtsi/MbpMmucd	MGI:6325139
ht2	Fkbp5^tm1b(KOMP)Wtsi/Fkbp5^+	C57BL/6N-Fkbp5^tm1b(KOMP)Wtsi/MbpMmucd	MGI:6461273

Genotype
MGI:6325139

hm1

• Allelic Composition: Fkbp5^{tm1b(KOMP)Wtsi}/Fkbp5^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Fkbp5^{tm1b(KOMP)Wtsi}/MbpMmucd
• Cell Lines: EPD0741_3_H03

Data Sources

IMPC Data for Fkbp5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased kidney weight ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased basophil cell number ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

immune system

increased basophil cell number ( J:211773 )

♂

IMPC - UCD

increased neutrophil cell number ( J:211773 )

♂

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

renal/urinary system

increased kidney weight ( J:211773 )

♂

IMPC - UCD

vision/eye

cornea opacity ( J:211773 )

♂

IMPC - UCD

Genotype
MGI:6461273

ht2

• Allelic Composition: Fkbp5^{tm1b(KOMP)Wtsi}/Fkbp5⁺
• Genetic Background: C57BL/6N-Fkbp5^{tm1b(KOMP)Wtsi}/MbpMmucd
• Cell Lines: EPD0741_3_H03

Data Sources

IMPC Data for Fkbp5

growth/size/body

increased lean body mass ( J:211773 )

IMPC - UCD

increased kidney weight ( J:211773 )

♂

IMPC - UCD

renal/urinary system

increased kidney weight ( J:211773 )

♂

IMPC - UCD