Phenotypes associated with this allele

• Allele Symbol: Ube2b^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5548336
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ube2b^tm1b(EUCOMM)Wtsi/Ube2b^tm1b(EUCOMM)Wtsi	C57BL/6N-Ube2b^tm1b(EUCOMM)Wtsi/Ics	MGI:5757839
ht2	Ube2b^tm1b(EUCOMM)Wtsi/Ube2b^+	C57BL/6N-Ube2b^tm1b(EUCOMM)Wtsi/Ics	MGI:5757838

Genotype
MGI:5757839

hm1

• Allelic Composition: Ube2b^{tm1b(EUCOMM)Wtsi}/Ube2b^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Ube2b^{tm1b(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0038_4_D01

Data Sources

IMPC Data for Ube2b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:5757838

ht2

• Allelic Composition: Ube2b^{tm1b(EUCOMM)Wtsi}/Ube2b⁺
• Genetic Background: C57BL/6N-Ube2b^{tm1b(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0038_4_D01

Data Sources

IMPC Data for Ube2b

behavior/neurological

limb grasping ( J:211773 )

♂

IMPC - HAR

abnormal gait ( J:211773 )

♂

IMPC - HAR

cardiovascular system

enlarged heart ( J:211773 )

IMPC - HAR

growth/size/body

enlarged heart ( J:211773 )

IMPC - HAR

hematopoietic system

decreased basophil cell number ( J:211773 )

♂

IMPC - HAR

decreased neutrophil cell number ( J:211773 )

IMPC - HAR

increased leukocyte cell number ( J:211773 )

♂

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

IMPC - HAR

immune system

decreased basophil cell number ( J:211773 )

♂

IMPC - HAR

decreased neutrophil cell number ( J:211773 )

IMPC - HAR

increased leukocyte cell number ( J:211773 )

♂

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

IMPC - HAR

integument

abnormal coat appearance ( J:211773 )

♂

IMPC - HAR