All Phenotypes Irak2<tm1.1Pcoh> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Irak2^tm1.1Pcoh
targeted mutation 1.1, Philip Cohen
MGI:5548123

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Irak1^tm1.1Pcoh/? Irak2^tm1.1Pcoh/?	involves: 129P2/OlaHsd * C57BL/6	MGI:5548134
ot2	Irak2^tm1.1Pcoh/?	involves: C57BL/6	MGI:5548131

Allelic Composition	Irak1^tm1.1Pcoh/? Irak2^tm1.1Pcoh/?
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irak1^tm1.1Pcoh mutation (0 available); any Irak1 mutation (16 available)
Irak2^tm1.1Pcoh mutation (0 available); any Irak2 mutation (58 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased interferon-alpha secretion ( J:205798 )

• from plasmacytoid dendritic cell stimulated with CpG-B, CpG-A or the TLR7 agonist poly(dU)

Allelic Composition	Irak2^tm1.1Pcoh/?
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irak2^tm1.1Pcoh mutation (0 available); any Irak2 mutation (58 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased interferon-alpha secretion ( J:205798 )

• from plasmacytoid dendritic cell stimulated with CpG-B, CpG-A or the TLR7 agonist poly(dU)

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