All Phenotypes Tek<tm1.1Vlcg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tek^tm1.1Vlcg
targeted mutation 1.1, Velocigene
MGI:5544795

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tek^tm1.1Vlcg/Tek^tm1.1Vlcg	involves: 129S6/SvEvTac * C57BL/6NTac	MGI:5546245
cn2	Tek^tm1.1Vlcg/Tek^tm1.1Vlcg Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/? Tg(tetO-cre)1Jaw/0	involves: 129 * C57BL/6NCr	MGI:5613966

Allelic Composition	Tek^tm1.1Vlcg/Tek^tm1.1Vlcg
Genetic Background	involves: 129S6/SvEvTac * C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tek^tm1.1Vlcg mutation (0 available); any Tek mutation (92 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:200671 )

Allelic Composition	Tek^tm1.1Vlcg/Tek^tm1.1Vlcg Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/? Tg(tetO-cre)1Jaw/0
Genetic Background	involves: 129 * C57BL/6NCr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy} mutation (5 available); any Gt(ROSA)26Sor mutation (942 available)
Tek^tm1.1Vlcg mutation (0 available); any Tek mutation (92 available)
Tg(tetO-cre)1Jaw mutation (5 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal anterior eye segment morphology ( J:217296 )

• in mice exposed to deoxycycline treatment at E16.5

increased cornea size ( J:217296 )

• enlarged

increased eye anterior chamber depth ( J:217296 )

• increased anterior chamber depth

buphthalmos ( J:217296 )

• eyes begin to protrude by 21 to 28 days of age in mice exposed to deoxycycline treatment at E16.5

• difficulty closing eyelids by 8 weeks of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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