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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dicer1tm2.1Vlcg
targeted mutation 2.1, Velocigene
MGI:5544770
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dicer1tm2.1Vlcg/Dicer1tm2.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546212
cn2
 		Dicer1tm1.1Vlcg/Dicer1tm2.1Vlcg
Tg(Nanog-cre)#Vlcg/0 		involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546213


Genotype
MGI:5546212
hm1
Allelic
Composition		 Dicer1tm2.1Vlcg/Dicer1tm2.1Vlcg
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dicer1tm2.1Vlcg mutation (0 available); any Dicer1 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:5546213
cn2
Allelic
Composition		 Dicer1tm1.1Vlcg/Dicer1tm2.1Vlcg
Tg(Nanog-cre)#Vlcg/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dicer1tm1.1Vlcg mutation (0 available); any Dicer1 mutation (94 available)
Dicer1tm2.1Vlcg mutation (0 available); any Dicer1 mutation (94 available)
Tg(Nanog-cre)#Vlcg mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:200671 )
• authors state that mice resemble Dicer1tm1Ghan

embryo
abnormal embryo development ( J:200671 )
• authors state that mice resemble Dicer1tm1Ghan




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory