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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nmnat2Gt(EUCE0262a08)1.1Hmgu
gene trap EUCE0262a08, 1.1, Helmholtz Zentrum Muenchen GmbH
MGI:5543590
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Nmnat2Gt(EUCE0262a08)1.1Hmgu/Nmnat2Gt(EUCE0262a08)1.1Hmgu involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL MGI:5543594
cn2
 		Nmnat2Gt(EUCE0262a08)1.1Hmgu/Nmnat2+ involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL MGI:5543595


Genotype
MGI:5543594
cn1
Allelic
Composition		 Nmnat2Gt(EUCE0262a08)1.1Hmgu/Nmnat2Gt(EUCE0262a08)1.1Hmgu
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nmnat2Gt(EUCE0262a08)1.1Hmgu mutation (0 available); any Nmnat2 mutation (272 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
axon degeneration ( J:200901 )
• in cultures of superior cervical ganglia explants, expression of cre results in robust dying-back degeneration of distal neurites




Genotype
MGI:5543595
cn2
Allelic
Composition		 Nmnat2Gt(EUCE0262a08)1.1Hmgu/Nmnat2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nmnat2Gt(EUCE0262a08)1.1Hmgu mutation (0 available); any Nmnat2 mutation (272 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
axon degeneration ( J:200901 )
• in cultures of superior cervical ganglia explants, expression of cre results in dying-back degeneration of distal neurites that is delayed compared to homozygous mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory