All Phenotypes Ank3<tm2.2Bnt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ank3^tm2.2Bnt
targeted mutation 2.2, Vann Bennett
MGI:5538266

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ank3^tm2.2Bnt/Ank3^tm2.2Bnt	involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB/N	MGI:5538268

Allelic Composition	Ank3^tm2.2Bnt/Ank3^tm2.2Bnt
Genetic Background	involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ank3^tm2.2Bnt mutation (0 available); any Ank3 mutation (172 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:198370 )

• Background Sensitivity: mice on a mixed 129 and C57BL/6 background do not survive beyond P2

prenatal lethality, incomplete penetrance ( J:198370 )

• Background Sensitivity: most mice die before birth on a more pure C57BL/6 background compared with mice on a mixed 129 and C57BL/6 backgrounds that survive to birth

renal/urinary system

abnormal kidney collecting duct epithelium morphology ( J:198370 )

• reduced lateral membrane height

respiratory system

abnormal bronchus epithelium morphology ( J:198370 )

• reduced lateral membrane height

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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