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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vhltm1.1Whkr
targeted mutation 1.1, Wilhelm Krek
MGI:5529337
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vhltm1.1Whkr/Vhltm1.1Whkr involves: 129S4/SvJae * C57BL/6 MGI:5529338


Genotype
MGI:5529338
hm1
Allelic
Composition		 Vhltm1.1Whkr/Vhltm1.1Whkr
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vhltm1.1Whkr mutation (0 available); any Vhl mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal intracellular organelle physiology ( J:198361 )
• mouse embryonic fibroblasts exhibit altered microtubule dynamics

liver/biliary system
liver/biliary system phenotype ( J:198361 )
N
• unlike tissue-specific knock-out mice, mice do not exhibit lipid accumulation in the liver or cavernous liver hemangiomas




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory