Phenotypes associated with this allele

• Allele Symbol: Cfb^{tm1.1(KOMP)Wtsi}
• Allele Name: targeted mutation 1.1, Wellcome Trust Sanger Institute
• Allele ID: MGI:5529069
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cfb^tm1.1(KOMP)Wtsi/Cfb^tm1.1(KOMP)Wtsi	C57BL/6N-Cfb^tm1.1(KOMP)Wtsi/J	MGI:5756863
hm2	Cfb^tm1.1(KOMP)Wtsi/Cfb^tm1.1(KOMP)Wtsi	C57BL/6N-Cfb^tm1.1(KOMP)Wtsi/Ucd	MGI:6262117

Genotype
MGI:5756863

hm1

• Allelic Composition: Cfb^{tm1.1(KOMP)Wtsi}/Cfb^{tm1.1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Cfb^{tm1.1(KOMP)Wtsi}/J
• Cell Lines: EPD0403_5_F06

Data Sources

IMPC Data for Cfb

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased erythrocyte cell number ( J:211773 )

♂

IMPC - JAX

increased hematocrit ( J:211773 )

♂

IMPC - JAX

increased hemoglobin content ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - JAX

decreased circulating phosphate level ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:6262117

hm2

• Allelic Composition: Cfb^{tm1.1(KOMP)Wtsi}/Cfb^{tm1.1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Cfb^{tm1.1(KOMP)Wtsi}/Ucd
• Cell Lines: EPD0403_5_F06

Data Sources

IMPC Data for Cfb

cardiovascular system

enlarged heart ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD