About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(DTA)Kio
targeted mutation 1, Dimitris Kioussis
MGI:5528898
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(DTA)Kio/Gt(ROSA)26Sor+
Tg(Tnfrsf4-cre)1Nik/0 		B6.129-Tnfrsf4tm2(cre)Nik Gt(ROSA)26Sortm1(DTA)Kio MGI:5529105


Genotype
MGI:5529105
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(DTA)Kio/Gt(ROSA)26Sor+
Tg(Tnfrsf4-cre)1Nik/0
Genetic
Background		 B6.129-Tnfrsf4tm2(cre)Nik Gt(ROSA)26Sortm1(DTA)Kio
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DTA)Kio mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
Tg(Tnfrsf4-cre)1Nik mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body size ( J:203905 )
• in a small proportion of mice as early as weaning
postnatal growth retardation ( J:203905 )
• in a small proportion of mice as early as weaning

endocrine/exocrine glands
exocrine pancreas atrophy ( J:203905 )
• without inflammatory infiltrates in a small proportion of mice

digestive/alimentary system
exocrine pancreas atrophy ( J:203905 )
• without inflammatory infiltrates in a small proportion of mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory