All Phenotypes Rag2<m1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rag2^m1Btlr
mutation 1, Bruce Beutler
MGI:5524145

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rag2^m1Btlr/Rag2^m1Btlr	C57BL/6J-Rag2^m1Btlr	MGI:5524158

Allelic Composition	Rag2^m1Btlr/Rag2^m1Btlr
Genetic Background	C57BL/6J-Rag2^m1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag2^m1Btlr mutation (1 available); any Rag2 mutation (115 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased B cell number ( J:203045 )

abnormal humoral immune response ( J:203045 )

• impaired T-dependent (T-D) and T-independent (T-I) humoral responses

decreased IgG level ( J:203045 )

• in response to OVA-Alum or beta-galactosidase

decreased IgM level ( J:203045 )

• in response to TNP-Ficoll

hematopoietic system

decreased B cell number ( J:203045 )

decreased IgG level ( J:203045 )

• in response to OVA-Alum or beta-galactosidase

decreased IgM level ( J:203045 )

• in response to TNP-Ficoll

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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