Analysis Tools
mortality/aging
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• no mice are recovered at birth when exposed to doxycycline throughout pregnancy
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reproductive system
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• mice treated with doxycycline from birth exhibit defective lobuloalveolar differentiation during mid- and late pregnancy that persists in parturition compared with wild-type mice
• however, alveolar lumina are filled with milk
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integument
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• of terminal end bud in mice treated with doxycycline from birth
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• at 4 and 6 weeks, mice treated with doxycycline from birth exhibit delayed mammary gland outgrowth compared with wild-type mice
• at 4 weeks, mice treated with doxycycline from birth exhibit distal ends without terminal end bud appearance unlike in wild-type mice
• however, outgrowth at 9 weeks and mammary epithelium architecture are normal
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• mice treated with doxycycline from birth exhibit defective lobuloalveolar differentiation during mid- and late pregnancy that persists in parturition compared with wild-type mice
• however, alveolar lumina are filled with milk
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• mice treated with doxycycline from birth exhibit reduced ductal elongation compared with wild-type mice
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growth/size/body
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• in mice treated with doxycycline from birth
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immune system
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• in mice treated with doxycycline from birth
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cellular
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• of terminal end bud in mice treated with doxycycline from birth
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endocrine/exocrine glands
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• of terminal end bud in mice treated with doxycycline from birth
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• at 4 and 6 weeks, mice treated with doxycycline from birth exhibit delayed mammary gland outgrowth compared with wild-type mice
• at 4 weeks, mice treated with doxycycline from birth exhibit distal ends without terminal end bud appearance unlike in wild-type mice
• however, outgrowth at 9 weeks and mammary epithelium architecture are normal
|
|
• mice treated with doxycycline from birth exhibit defective lobuloalveolar differentiation during mid- and late pregnancy that persists in parturition compared with wild-type mice
• however, alveolar lumina are filled with milk
|
|
• mice treated with doxycycline from birth exhibit reduced ductal elongation compared with wild-type mice
|
