Phenotypes associated with this allele

• Allele Symbol: Cgn^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5521541
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cgn^tm1b(KOMP)Wtsi/Cgn^tm1b(KOMP)Wtsi	B6N(Cg)-Cgn^tm1b(KOMP)Wtsi/J	MGI:5630963
ht2	Cgn^tm1b(KOMP)Wtsi/Cgn^+	B6N(Cg)-Cgn^tm1b(KOMP)Wtsi/J	MGI:5759145

Genotype
MGI:5630963

hm1

• Allelic Composition: Cgn^{tm1b(KOMP)Wtsi}/Cgn^{tm1b(KOMP)Wtsi}
• Genetic Background: B6N(Cg)-Cgn^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0161_2_C01

Data Sources

IMPC Data for Cgn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - JAX

embryo

abnormal embryo size ( J:211773 )

IMPC - JAX

abnormal neural tube closure ( J:211773 )

♀

IMPC - JAX

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - JAX

homeostasis/metabolism

cyanosis ( J:211773 )

♀

IMPC - JAX

limbs/digits/tail

abnormal tail morphology ( J:211773 )

♀

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

nervous system

abnormal neural tube closure ( J:211773 )

♀

IMPC - JAX

abnormal forebrain morphology ( J:211773 )

♀

IMPC - JAX

Genotype
MGI:5759145

ht2

• Allelic Composition: Cgn^{tm1b(KOMP)Wtsi}/Cgn⁺
• Genetic Background: B6N(Cg)-Cgn^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0161_2_C01

Data Sources

IMPC Data for Cgn

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - JAX