Phenotypes associated with this allele

• Allele Symbol: Srd5a3^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5520177
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Srd5a3^tm1b(EUCOMM)Wtsi/Srd5a3^tm1b(EUCOMM)Wtsi	B6N(Cg)-Srd5a3^tm1b(EUCOMM)Wtsi/J	MGI:5763855
ht2	Srd5a3^tm1b(EUCOMM)Wtsi/Srd5a3^+	B6N(Cg)-Srd5a3^tm1b(EUCOMM)Wtsi/J	MGI:5767813

Genotype
MGI:5763855

hm1

• Allelic Composition: Srd5a3^{tm1b(EUCOMM)Wtsi}/Srd5a3^{tm1b(EUCOMM)Wtsi}
• Genetic Background: B6N(Cg)-Srd5a3^{tm1b(EUCOMM)Wtsi}/J
• Cell Lines: EPD0575_2_B02

Data Sources

IMPC Data for Srd5a3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo turning ( J:211773 )

IMPC - JAX

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

abnormal tail bud morphology ( J:211773 )

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

limbs/digits/tail

abnormal tail bud morphology ( J:211773 )

IMPC - JAX

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5767813

ht2

• Allelic Composition: Srd5a3^{tm1b(EUCOMM)Wtsi}/Srd5a3⁺
• Genetic Background: B6N(Cg)-Srd5a3^{tm1b(EUCOMM)Wtsi}/J
• Cell Lines: EPD0575_2_B02

Data Sources

IMPC Data for Srd5a3

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - JAX