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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mbnl3tm1.1Sws
targeted mutation 1.1, Maurice S Swanson
MGI:5518844
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mbnl3tm1.1Sws/Mbnl3tm1.1Sws involves: BALB/c * C57BL/6 * C57BL/6J MGI:5518852
ot2
 		Mbnl3tm1.1Sws/Y involves: BALB/c * C57BL/6 * C57BL/6J MGI:5518853


Genotype
MGI:5518852
hm1
Allelic
Composition		 Mbnl3tm1.1Sws/Mbnl3tm1.1Sws
Genetic
Background		 involves: BALB/c * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mbnl3tm1.1Sws mutation (0 available); any Mbnl3 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
decreased skeletal muscle fiber size ( J:199127 )
• decreased cross-sectional area in mice treated with notexin
decreased skeletal muscle fiber number ( J:199127 )
• in mice treated with notexin
impaired skeletal muscle regeneration ( J:199127 )
• progressive impairment in older mice injected with notexin

behavior/neurological
decreased grip strength ( J:199127 )
• in mice treated with notexin




Genotype
MGI:5518853
ot2
Allelic
Composition		 Mbnl3tm1.1Sws/Y
Genetic
Background		 involves: BALB/c * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mbnl3tm1.1Sws mutation (0 available); any Mbnl3 mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
decreased skeletal muscle fiber size ( J:199127 )
• decreased cross-sectional area in mice treated with notexin
decreased skeletal muscle fiber number ( J:199127 )
• in mice treated with notexin
impaired skeletal muscle regeneration ( J:199127 )
• progressive impairment in older mice injected with notexin

behavior/neurological
decreased grip strength ( J:199127 )
• in mice treated with notexin




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory