mortality/aging
• homozygous embryos are recovered at expected Mendelian ratios at E7.5 but stall in development at ~E8.0
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• no homozygous embryos are recovered at E9.5
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embryo
• embryos stall in development at ~E8.0 and are significantly delayed by E8.5
• however, most morphological features typical of E7.5 are present
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• embryos appear slightly smaller than controls at E7.5
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growth/size/body
• embryos stall in development at ~E8.0 and are significantly delayed by E8.5
• however, most morphological features typical of E7.5 are present
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• embryos appear slightly smaller than controls at E7.5
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