Phenotypes associated with this allele

• Allele Symbol: Psen1^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5515627
• Summary: 4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Psen1^tm1.1(KOMP)Vlcg/Psen1^tm1.1(KOMP)Vlcg	C57BL/6N-Psen1^tm1.1(KOMP)Vlcg/J	MGI:5631447
hm2	Psen1^tm1.1(KOMP)Vlcg/Psen1^tm1.1(KOMP)Vlcg	C57BL/6N-Psen1^tm1.1(KOMP)Vlcg/Ucd	MGI:5757576
ht3	Psen1^tm1.1(KOMP)Vlcg/Psen1^+	C57BL/6N-Psen1^tm1.1(KOMP)Vlcg/J	MGI:5759413
ht4	Psen1^tm1.1(KOMP)Vlcg/Psen1^+	C57BL/6N-Psen1^tm1.1(KOMP)Vlcg/Ucd	MGI:5797742

Genotype
MGI:5631447

hm1

• Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 15671A-D10

Data Sources

IMPC Data for Psen1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - JAX

cardiovascular system

hemorrhage ( J:211773 )

IMPC - JAX

homeostasis/metabolism

cyanosis ( J:211773 )

IMPC - JAX

edema ( J:211773 )

IMPC - JAX

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - JAX

abnormal tail morphology ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5757576

hm2

• Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 15671A-D10

Data Sources

IMPC Data for Psen1

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - TCP

abnormal tail morphology ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:5759413

ht3

• Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1⁺
• Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 15671A-D10

Data Sources

IMPC Data for Psen1

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:5797742

ht4

• Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1⁺
• Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
• Cell Lines: 15671A-D10

Data Sources

IMPC Data for Psen1

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP