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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Plce1tm2Avsm
targeted mutation 2, Alan V Smrcka
MGI:5514168
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Plce1tm2Avsm/Plce1tm2Avsm
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ 		involves: 129S6/SvEvTac * C57BL/6 * FVB/N MGI:5514169


Genotype
MGI:5514169
cn1
Allelic
Composition		 Plce1tm2Avsm/Plce1tm2Avsm
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A1cfTg(Myh6-cre/Esr1*)1Jmk mutation (5 available); any A1cf mutation (37 available)
Plce1tm2Avsm mutation (0 available); any Plce1 mutation (115 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased response of heart to induced stress ( J:197247 )
• following transverse aortic constriction, mice exhibit diminished cardiac hypertrophy compared with control mice

homeostasis/metabolism
decreased response of heart to induced stress ( J:197247 )
• following transverse aortic constriction, mice exhibit diminished cardiac hypertrophy compared with control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory