Phenotypes associated with this allele

• Allele Symbol: Wee1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5513834
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wee1^tm1b(EUCOMM)Wtsi/Wee1^tm1b(EUCOMM)Wtsi	C57BL/6N-Wee1^tm1b(EUCOMM)Wtsi/Tcp	MGI:5757886
ht2	Wee1^tm1b(EUCOMM)Wtsi/Wee1^+	C57BL/6N-Wee1^tm1b(EUCOMM)Wtsi/Tcp	MGI:5797911

Genotype
MGI:5757886

hm1

• Allelic Composition: Wee1^{tm1b(EUCOMM)Wtsi}/Wee1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Wee1^{tm1b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0636_5_C05

Data Sources

IMPC Data for Wee1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5797911

ht2

• Allelic Composition: Wee1^{tm1b(EUCOMM)Wtsi}/Wee1⁺
• Genetic Background: C57BL/6N-Wee1^{tm1b(EUCOMM)Wtsi}/Tcp
• Cell Lines: EPD0636_5_C05

Data Sources

IMPC Data for Wee1

hematopoietic system

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - TCP

decreased mean corpuscular hemoglobin concentration ( J:211773 )

IMPC - TCP

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - TCP