Phenotypes associated with this allele

• Allele Symbol: Dtnbp1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5513769
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dtnbp1^tm1b(EUCOMM)Hmgu/Dtnbp1^tm1b(EUCOMM)Hmgu	C57BL/6N-Dtnbp1^tm1b(EUCOMM)Hmgu/Tcp	MGI:5757025

Genotype
MGI:5757025

hm1

• Allelic Composition: Dtnbp1^{tm1b(EUCOMM)Hmgu}/Dtnbp1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Dtnbp1^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0526_5_C05

Data Sources

IMPC Data for Dtnbp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

♀

IMPC - TCP

hematopoietic system

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased neutrophil cell number ( J:211773 )

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - TCP

increased circulating phosphate level ( J:211773 )

IMPC - TCP

immune system

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased neutrophil cell number ( J:211773 )

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♀

IMPC - TCP

integument

abnormal coat/hair pigmentation ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

♂

IMPC - TCP

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

IMPC - TCP

abnormal iris pigmentation ( J:211773 )

IMPC - TCP

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - TCP

vision/eye

abnormal iris pigmentation ( J:211773 )

IMPC - TCP

abnormal retina morphology ( J:211773 )

IMPC - TCP