All Phenotypes Pip5k1c<tm2.1Ref> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pip5k1c^tm2.1Ref
targeted mutation 2.1, Reinhard Fassler
MGI:5509203

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pip5k1c^tm2.1Ref/Pip5k1c^tm2.1Ref	B6.129-Pip5k1c^tm2.1Ref	MGI:5509217

Allelic Composition	Pip5k1c^tm2.1Ref/Pip5k1c^tm2.1Ref
Genetic Background	B6.129-Pip5k1c^tm2.1Ref

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pip5k1c^tm2.1Ref mutation (0 available); any Pip5k1c mutation (42 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:200273 )

nervous system

abnormal synaptic vesicle recycling ( J:200273 )

• defective synaptic vesicle endocytosis

behavior/neurological

absent gastric milk in neonates ( J:200273 )

cellular

abnormal cell physiology ( J:200273 )

• agonist-induced calcium signaling is reduced in fibroblasts compared with wild-type cells

integument

integument phenotype ( J:200273 )

N	• mice exhibit normal epithelial integrity

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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