Phenotypes associated with this allele

• Allele Symbol: Grin2b^tm1.1Nhk
• Allele Name: targeted mutation 1.1, Noboru H Komiyama
• Allele ID: MGI:5505780
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grin2b^tm1.1Nhk/Grin2b^tm1.1Nhk	involves: 129P2/OlaHsd * C57BL/6J	MGI:5505864

Genotype
MGI:5505864

hm1

• Allelic Composition: Grin2b^tm1.1Nhk/Grin2b^tm1.1Nhk
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal operant conditioning behavior ( J:197485 )

• mice require more trials to reach criterion compared with wild-type mice

decreased anxiety-related response ( J:197485 )

• in an elevated plus maze, mice spend more time in open arms compared with wild-type mice

• in an open field, mice travel take less time to enter the inner zone compared with wild-type mice

impaired coordination ( J:197485 )

nervous system

nervous system phenotype ( J:197485 )

N • mice exhibit normal barrel field in the somatosensory cortex

enhanced long-term potentiation ( J:197485 )

• following theta burst stimulation

reduced long-term potentiation ( J:197485 )

• following theta pulse stimulation