Phenotypes associated with this allele

• Allele Symbol: Carm1^m9Bei
• Allele Name: mutation 9, David R Beier
• Allele ID: MGI:5505489
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Carm1^m9Bei/Carm1^m9Bei	involves: A/J * C57BL/6	MGI:5505491
hm2	Carm1^m9Bei/Carm1^m9Bei	involves: A/J * C57BL/6J	MGI:7328983

Genotype
MGI:5505491

hm1

• Allelic Composition: Carm1^m9Bei/Carm1^m9Bei
• Genetic Background: involves: A/J * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal corpus callosum morphology ( J:199782 )

• occasional Probst bundles in the corpus callosum

craniofacial

abnormal craniofacial morphology ( J:199782 )

cleft palate ( J:199782 )

growth/size/body

cleft palate ( J:199782 )

decreased embryo size ( J:199782 )

omphalocele ( J:199782 )

limbs/digits/tail

abnormal limb morphology ( J:199782 )

embryo

decreased embryo size ( J:199782 )

digestive/alimentary system

cleft palate ( J:199782 )

Genotype
MGI:7328983

hm2

• Allelic Composition: Carm1^m9Bei/Carm1^m9Bei
• Genetic Background: involves: A/J * C57BL/6J

cardiovascular system

persistent truncus arteriosus ( J:327081 )

• in E12.5 embryos

increased atrioventricular cushion size ( J:327081 )

• growing into and obstructing mitral valve in E12.5 embryos

double outlet right ventricle ( J:327081 )

• in E18.5 embryos

increased heart right atrium size ( J:327081 )

• in E12.5 embryos

abnormal heart left atrium morphology ( J:327081 )

• torn atrium, leading to thoracic bleeding in E12.5 embryos

heart left atrium hypoplasia ( J:327081 )

• in E12.5 embryos

ventricular septal defect ( J:327081 )

• in E18.5 embryos

hemothorax ( J:327081 )

• bleeding in thoracic cavity in E12.5 embryos owing to torn left atrium

heart hemorrhage ( J:327081 )

• blood pooling in left atrium in E12.5 embryos

craniofacial

abnormal craniofacial morphology ( J:327081 )

• in E18.5 embryos

cleft palate ( J:327081 )

• in E18.5 embryos

digestive/alimentary system

cleft palate ( J:327081 )

• in E18.5 embryos

embryo

decreased embryo size ( J:327081 )

• in E18.5 embryos

growth/size/body

cleft palate ( J:327081 )

• in E18.5 embryos

decreased embryo size ( J:327081 )

• in E18.5 embryos

omphalocele ( J:327081 )

• in E18.5 embryos

limbs/digits/tail

abnormal limb morphology ( J:327081 )

• in E18.5 embryos

mortality/aging

preweaning lethality, complete penetrance ( J:327081 )

• reduced Mendelian frequency at E18.5; no mice survive beyond weaning

respiratory system

hemothorax ( J:327081 )

• bleeding in thoracic cavity in E12.5 embryos owing to torn left atrium