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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Drc3m6Bei
mutation 6, David R Beier
MGI:5505445
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Drc3m6Bei/Drc3m6Bei
Rgs4tm1Dgen/Rgs4+ 		involves: 129P2/OlaHsd * A/J * C57BL/6 MGI:5505455


Genotype
MGI:5505455
cx1
Allelic
Composition		 Drc3m6Bei/Drc3m6Bei
Rgs4tm1Dgen/Rgs4+
Genetic
Background		 involves: 129P2/OlaHsd * A/J * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Drc3m6Bei mutation (1 available); any Drc3 mutation (25 available)
Rgs4tm1Dgen mutation (1 available); any Rgs4 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:199782 )
• postnatal lethality in the third week sometimes

nervous system
enlarged lateral ventricles ( J:199782 )
• ventriculomegaly
abnormal hippocampus morphology ( J:199782 )
• posteriorly displaced
thin cerebral cortex ( J:199782 )
• severe cortical thinning

craniofacial
domed cranium ( J:199782 )
• domed heads sometimes

skeleton
domed cranium ( J:199782 )
• domed heads sometimes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory