Analysis Tools
mortality/aging
|
• homozygotes die shortly after birth
|
growth/size/body
|
• kidney development is normal through E15.5
• glomerular cysts begin to appear by E16.5
• fewer cysts than in mice with the juvenile cystic kidney mutation
|
|
• in about 2/3 of mice displaying right pulmonary isomerism
|
|
• left lung with four lobes as seen in the right lung - in about 61% of mice
|
|
• in about 24% of mice
• 15% of mice are normal
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cardiovascular system
|
• in some mice
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hemorrhage
(
J:199559
)
|
• focal hemorrhage frequently seen at mid gestation
|
homeostasis/metabolism
renal/urinary system
|
• kidney development is normal through E15.5
• glomerular cysts begin to appear by E16.5
• fewer cysts than in mice with the juvenile cystic kidney mutation
|
|
• tubules have thin walls and are slightly dilated at birth
• tubules are not dilated at E18.5
|
respiratory system
|
• left lung with four lobes as seen in the right lung - in about 61% of mice
|
