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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(tetO-Tfrc/EGFP/Ova)#Sfz
transgene insertion, Steven Ziegler
MGI:5503055
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(KRT5-rtTA)1Glk/0
Tg(tetO-Tfrc/EGFP/Ova)#Sfz/0
Tg(tetO/CMV-Tslp)#Sfz/0 		involves: C3H * C57BL/6 * FVB/N MGI:5503059
cx2
 		Tg(KRT5-rtTA)1Glk/0
Tg(tetO-Tfrc/EGFP/Ova)#Sfz/0 		involves: FVB/N MGI:5503058


Genotype
MGI:5503059
cx1
Allelic
Composition		 Tg(KRT5-rtTA)1Glk/0
Tg(tetO-Tfrc/EGFP/Ova)#Sfz/0
Tg(tetO/CMV-Tslp)#Sfz/0
Genetic
Background		 involves: C3H * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased T cell proliferation ( J:199558 )
• of ovalbumin-specific CD4 T cells in doxycycline-treated mice unlike when cells are transferred into control mice
respiratory system inflammation ( J:199558 )
• airway inflammation in doxycycline-treated mice treated intranasally with ovalbumin
skin inflammation ( J:199558 )
• eczematous inflammation in the skin of doxycycline- and anti-mTSLP antibody-treated mice

integument
skin inflammation ( J:199558 )
• eczematous inflammation in the skin of doxycycline- and anti-mTSLP antibody-treated mice

respiratory system
respiratory system inflammation ( J:199558 )
• airway inflammation in doxycycline-treated mice treated intranasally with ovalbumin

hematopoietic system
increased T cell proliferation ( J:199558 )
• of ovalbumin-specific CD4 T cells in doxycycline-treated mice unlike when cells are transferred into control mice

cellular
increased T cell proliferation ( J:199558 )
• of ovalbumin-specific CD4 T cells in doxycycline-treated mice unlike when cells are transferred into control mice




Genotype
MGI:5503058
cx2
Allelic
Composition		 Tg(KRT5-rtTA)1Glk/0
Tg(tetO-Tfrc/EGFP/Ova)#Sfz/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:199558 )
N
• doxycycline- and anti-mTSLP antibody-treated mice do not exhibit eczematous inflammation

integument
integument phenotype ( J:199558 )
N
• doxycycline- and anti-mTSLP antibody-treated mice do not exhibit eczematous inflammation




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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory