Phenotypes associated with this allele

• Allele Symbol: Ptf1a/Ptf1aos^{tm2(Ptf1a)Kymm}
• Allele Name: targeted mutation 2, Ken-ichi Yamamura
• Allele ID: MGI:5502956
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Etn2^Sd/Etn2^Sd Ptf1a/Ptf1aos^tm2(Ptf1a)Kymm/Ptf1a/Ptf1aos^tm2(Ptf1a)Kymm	involves: C57BL/6	MGI:5508340
cx2	Etn2^Sd/Etn2^+ Ptf1a/Ptf1aos^tm2(Ptf1a)Kymm/Ptf1a^+	involves: C57BL/6	MGI:5508353

Genotype
MGI:5508340

cx1

• Allelic Composition: Etn2^Sd/Etn2^Sd; Ptf1a/Ptf1aos^{tm2(Ptf1a)Kymm}/Ptf1a/Ptf1aos^{tm2(Ptf1a)Kymm}
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal anus morphology ( J:195133 )

• anorectal malformation as in Etn2^Sd homozygotes

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:195133 )

N • normal pancreas

growth/size/body

decreased body length ( J:195133 )

• in neonates

limbs/digits/tail

absent tail ( J:195133 )

• in neonates

skeleton

abnormal nucleus pulposus morphology ( J:195133 )

• of intervertebral discs as in Etn2^Sd homozygotes

short vertebral column ( J:195133 )

• truncated at the tenth thoracic vertebrae

Genotype
MGI:5508353

cx2

• Allelic Composition: Etn2^Sd/Etn2⁺; Ptf1a/Ptf1aos^{tm2(Ptf1a)Kymm}/Ptf1a⁺
• Genetic Background: involves: C57BL/6

limbs/digits/tail

short tail ( J:195133 )

skeleton

short vertebral column ( J:195133 )

• truncated at the eighth cervical vertebrae