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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Srxn1tm1Mtol
targeted mutation 1, Mireille B Toledano
MGI:5501480
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Srxn1tm1Mtol/Srxn1tm1Mtol either: B6.129S2-Srxn1tm1Mtol or (involves: 129S2/SvPasCrl * C57BL/6) MGI:5501508


Genotype
MGI:5501508
hm1
Allelic
Composition
Srxn1tm1Mtol/Srxn1tm1Mtol
Genetic
Background
either: B6.129S2-Srxn1tm1Mtol or (involves: 129S2/SvPasCrl * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srxn1tm1Mtol mutation (0 available); any Srxn1 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice treated with LPS exhibit increased lethality compared with wild-type mice

homeostasis/metabolism
• mice treated with LPS exhibit increased lethality compared with wild-type mice

immune system
• mice treated with LPS exhibit increased lethality and alanine and aspartate transaminase levels compared with wild-type mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory