Phenotypes associated with this allele

• Allele Symbol: Oasl1^tm1Yjk
• Allele Name: targeted mutation 1, Young-Joon Kim
• Allele ID: MGI:5498949
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Oasl1^tm1Yjk/Oasl1^tm1Yjk	B6.129P2-Oasl1^tm1Yjk	MGI:5498951

Genotype
MGI:5498951

hm1

• Allelic Composition: Oasl1^tm1Yjk/Oasl1^tm1Yjk
• Genetic Background: B6.129P2-Oasl1^tm1Yjk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal circulating interferon level ( J:194467 )

• increased expression of type I interferon when stimulated by poly (I:C) or by RNA virus encephalomyocarditis virus

decreased susceptibility to Picornaviridae infection ( J:194467 )

• mice are more resistant to viral infections

• more rapid clearing of virus than in controls

decreased susceptibility to Picornaviridae infection induced morbidity/mortality ( J:194467 )

• survival rates are improved

homeostasis/metabolism

abnormal circulating interferon level ( J:194467 )

• increased expression of type I interferon when stimulated by poly (I:C) or by RNA virus encephalomyocarditis virus

mortality/aging

decreased susceptibility to Picornaviridae infection induced morbidity/mortality ( J:194467 )

• survival rates are improved