All Phenotypes Ceacam1<tm1.1Fta> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ceacam1^tm1.1Fta
targeted mutation 1.1, Fumihiro Taguchi
MGI:5496530

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ceacam1^tm1.1Fta/Ceacam1^tm1.1Fta	C57BL/6(FVB)-Ceacam1^tm1.1Fta	MGI:5496535

Allelic Composition	Ceacam1^tm1.1Fta/Ceacam1^tm1.1Fta
Genetic Background	C57BL/6(FVB)-Ceacam1^tm1.1Fta

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ceacam1^tm1.1Fta mutation (0 available); any Ceacam1 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased susceptibility to Coronaviridae infection induced morbidity/mortality ( J:198335 )

• mice are resistant to mouse hepatitis virus (MHV) infection unlike C57BL/6 controls but similar to SJL mice

immune system

decreased susceptibility to Coronaviridae infection ( J:198335 )

• infection with mouse hepatitis virus (MHV A59) infection are fully resistant to lethality and viral accumulation observed in C57BL/6 control mice

• MHV fails to replicate in peritoneal macrophages

decreased susceptibility to Coronaviridae infection induced morbidity/mortality ( J:198335 )

• mice are resistant to mouse hepatitis virus (MHV) infection unlike C57BL/6 controls but similar to SJL mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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