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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfp277tm1Aiwa
targeted mutation 1, Atsushi Iwama
MGI:5496522
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zfp277tm1Aiwa/Zfp277tm1Aiwa involves: 129S1/Sv * 129X1/SvJ MGI:5496526


Genotype
MGI:5496526
hm1
Allelic
Composition		 Zfp277tm1Aiwa/Zfp277tm1Aiwa
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp277tm1Aiwa mutation (0 available); any Zfp277 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
early cellular replicative senescence ( J:198334 )
• in mouse embryonic fibroblasts at passage 6
• however, replication is rescued by HPV-16 E6 expression




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory