Phenotypes associated with this allele

• Allele Symbol: H2bc21^tm1Dlc
• Allele Name: targeted mutation 1, Catherine Dulac
• Allele ID: MGI:5495670
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	H2bc21^tm1Dlc/H2bc21^tm1Dlc	involves: 129S4/SvJae * C57BL/6	MGI:5495679

Genotype
MGI:5495679

hm1

• Allelic Composition: H2bc21^tm1Dlc/H2bc21^tm1Dlc
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased neuron apoptosis ( J:197878 )

• in mature olfactory neurons

abnormal olfactory sensory neuron morphology ( J:197878 )

• increased lifespan

taste/olfaction

abnormal olfactory sensory neuron morphology ( J:197878 )

• increased lifespan

impaired olfaction ( J:197878 )

• in an odor discrimination test, mice learn more slowly than wild-type mice

• however, mice exhibit normal odor-evoking, number of olfactory glomeruli and ordorant receptor switching

cellular

decreased neuron apoptosis ( J:197878 )

• in mature olfactory neurons

craniofacial

abnormal olfactory sensory neuron morphology ( J:197878 )

• increased lifespan

respiratory system

abnormal olfactory sensory neuron morphology ( J:197878 )

• increased lifespan

growth/size/body

abnormal olfactory sensory neuron morphology ( J:197878 )

• increased lifespan