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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Syne4tm1Kare
targeted mutation 1, Karen B Avraham
MGI:5494678
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Syne4tm1Kare/Syne4tm1Kare involves: C57BL/6 MGI:5494680


Genotype
MGI:5494680
hm1
Allelic
Composition		 Syne4tm1Kare/Syne4tm1Kare
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Syne4tm1Kare mutation (0 available); any Syne4 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal cochlear outer hair cell morphology ( J:194486 )
• outer hair cells exhibit abnormal positioning of the nucleus compared with wild-type mice

nervous system
abnormal cochlear outer hair cell morphology ( J:194486 )
• outer hair cells exhibit abnormal positioning of the nucleus compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory