Phenotypes associated with this allele

• Allele Symbol: Cacna1s^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5494476
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cacna1s^tm1.1(KOMP)Vlcg/Cacna1s^tm1.1(KOMP)Vlcg	B6N(Cg)-Cacna1s^tm1.1(KOMP)Vlcg/J	MGI:5630922
ht2	Cacna1s^tm1.1(KOMP)Vlcg/Cacna1s^+	B6N(Cg)-Cacna1s^tm1.1(KOMP)Vlcg/J	MGI:5608251

Genotype
MGI:5630922

hm1

• Allelic Composition: Cacna1s^{tm1.1(KOMP)Vlcg}/Cacna1s^{tm1.1(KOMP)Vlcg}
• Genetic Background: B6N(Cg)-Cacna1s^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 14596A-D6

Data Sources

IMPC Data for Cacna1s

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - JAX

cardiovascular system

abnormal placenta vasculature ( J:211773 )

IMPC - JAX

hemorrhage ( J:211773 )

IMPC - JAX

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - JAX

embryo

abnormal placenta vasculature ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

homeostasis/metabolism

cyanosis ( J:211773 )

IMPC - JAX

edema ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

respiratory system

respiratory system phenotype ( J:211773 )

IMPC - JAX

Genotype
MGI:5608251

ht2

• Allelic Composition: Cacna1s^{tm1.1(KOMP)Vlcg}/Cacna1s⁺
• Genetic Background: B6N(Cg)-Cacna1s^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 14596A-D6

Data Sources

IMPC Data for Cacna1s

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - JAX