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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ntrk2tm2.1Ddg
targeted mutation 2.1, David D Ginty
MGI:5490140
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ntrk2tm2.1Ddg/Ntrk2tm2.1Ddg involves: 129P2/OlaHsd MGI:5617024
hm2
Ntrk2tm2.1Ddg/Ntrk2tm2.1Ddg involves: 129S6/SvEvTac MGI:5617032
hm3
Ntrk2tm2.1Ddg/Ntrk2tm2.1Ddg involves: 129S6/SvEvTac * C57BL/6 MGI:5490142


Genotype
MGI:5617024
hm1
Allelic
Composition
Ntrk2tm2.1Ddg/Ntrk2tm2.1Ddg
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk2tm2.1Ddg mutation (1 available); any Ntrk2 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• at E12, male and female mice exhibit impaired initial axonal projections in the mammary gland compared with wild-type mice
• at E13, female mice exhibit reduced sensory neurons innervation of the mammary gland rudiments compared with wild-type mice




Genotype
MGI:5617032
hm2
Allelic
Composition
Ntrk2tm2.1Ddg/Ntrk2tm2.1Ddg
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk2tm2.1Ddg mutation (1 available); any Ntrk2 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice are not viable




Genotype
MGI:5490142
hm3
Allelic
Composition
Ntrk2tm2.1Ddg/Ntrk2tm2.1Ddg
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntrk2tm2.1Ddg mutation (1 available); any Ntrk2 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory