Phenotypes associated with this allele

• Allele Symbol: Sum4^M1Jus
• Allele Name: mutation 1, Monica J Justice
• Allele ID: MGI:5489915
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Mecp2^tm1.1Bird/Y Sum4^M1Jus/Sum4^+	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J	MGI:5499847

Genotype
MGI:5499847

cx1

• Allelic Composition: Mecp2^tm1.1Bird/Y; Sum4^M1Jus/Sum4⁺
• Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

extended life span ( J:198551 )

• lifespan in increased at least 3 weeks from the average 50% lethality time point of Mecp2^tm1.1Bird hemizygotes

behavior/neurological

lethargy ( J:198551 )

• at 20 weeks but ameliorated compared to in Mecp2^tm1.1Bird hemizygotes

limb grasping ( J:198551 )

• at 8 and 20 weeks but ameliorated compared to in Mecp2^tm1.1Bird hemizygotes

tremors ( J:198551 )

• at 8 and 20 weeks but ameliorated compared to in Mecp2^tm1.1Bird hemizygotes

craniofacial

malocclusion ( J:198551 )

• as in Mecp2^tm1.1Bird hemizygotes

growth/size/body

growth/size/body region phenotype ( J:198551 )

N • normal body weight unlike Mecp2^tm1.1Bird hemizygotes

malocclusion ( J:198551 )

• as in Mecp2^tm1.1Bird hemizygotes

immune system

eye inflammation ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes

dermatitis ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes

skeleton

malocclusion ( J:198551 )

• as in Mecp2^tm1.1Bird hemizygotes

integument

dermatitis ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes

vision/eye

eye inflammation ( J:198551 )

• unlike Mecp2^tm1.1Bird hemizygotes