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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Krt7tm1Whim
targeted mutation 1, William Henry Irwin McLean
MGI:5488745
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Krt7tm1Whim/Krt7tm1Whim involves: 129P2/OlaHsd * C57BL/6 MGI:5488755


Genotype
MGI:5488755
hm1
Allelic
Composition		 Krt7tm1Whim/Krt7tm1Whim
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krt7tm1Whim mutation (0 available); any Krt7 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Hyperproliferation of the bladder urothelium in Krt7tm1Whim/Krt7tm1Whim mice

renal/urinary system
abnormal urinary bladder physiology ( J:196575 )
• 5-fold increase in the proliferation of urothelial cells without any histological evidence of hyperplasia

cellular
increased cell proliferation ( J:196575 )
• 5-fold increase in the proliferation of urothelial cells without any histological evidence of hyperplasia




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory