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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zbtb7btm4.1Itan
targeted mutation 4.1, Ichiro Taniuchi
MGI:5486334
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zbtb7btm4.1Itan/Zbtb7btm4.1Itan Not Specified MGI:5486339
cx2
 		B2mtm1Unc/B2mtm1Unc
Zbtb7btm4.1Itan/Zbtb7btm4.1Itan 		involves: 129P2/OlaHsd MGI:5486340


Genotype
MGI:5486339
hm1
Allelic
Composition		 Zbtb7btm4.1Itan/Zbtb7btm4.1Itan
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zbtb7btm4.1Itan mutation (0 available); any Zbtb7b mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system

hematopoietic system




Genotype
MGI:5486340
cx2
Allelic
Composition		 B2mtm1Unc/B2mtm1Unc
Zbtb7btm4.1Itan/Zbtb7btm4.1Itan
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2mtm1Unc mutation (36 available); any B2m mutation (117 available)
Zbtb7btm4.1Itan mutation (0 available); any Zbtb7b mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased CD8-positive, alpha-beta T cell number ( J:193321 )
• mature CD8+ T cells are increased unlike controls

hematopoietic system
increased CD8-positive, alpha-beta T cell number ( J:193321 )
• mature CD8+ T cells are increased unlike controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory