Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Id2tm1Gtbz mutation
(0 available);
any
Id2 mutation
(19 available)
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normal phenotype
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• mice exhibit normal survival and hematopoietic cellularity and lineage composition
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Batf3tm1Kmm mutation
(4 available);
any
Batf3 mutation
(17 available)
Id2tm1Gtbz mutation
(0 available);
any
Id2 mutation
(19 available)
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immune system
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• in reconstitution assays, CD8alpha+ dendritic cells generate from transplanted bone marrow cells fail to survive long-term
• CD8alpha+ dendritic cells exhibit impaired cell-associated cross-presentation compared with control cells
• however, cells exhibit normal soluble cross-presentation and cell-associated antigen cross-presentation during GVHD or HSV-1 viral antigens
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Id2tm1Gtbz mutation
(0 available);
any
Id2 mutation
(19 available)
Irf8tm1Hor mutation
(1 available);
any
Irf8 mutation
(32 available)
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hematopoietic system
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• in reconstitution assays, bone marrow cells are not able to generate CD8alpha+ dendritic cells
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Id2tm1Gtbz mutation
(0 available);
any
Id2 mutation
(19 available)
Nfil3tm1.1Brad mutation
(0 available);
any
Nfil3 mutation
(31 available)
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hematopoietic system
N |
• in reconstitution assays, bone marrow cells are able to generate CD8alpha+ dendritic cells
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immune system
N |
• in reconstitution assays, bone marrow cells are able to generate CD8alpha+ dendritic cells
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